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RESEARCH USE ONLY:
All products listed on this site are for research purposes ONLY. This product is NOT intended for human or animal consumption of any kind, and subject to our Terms and Conditions.
Lyophilized powder sealed in an airtight vial. Lyophilization enhances peptide stability during storage.
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in all living cells and is the active form of Vitamin B3.
- It plays two major roles:
- Participating in redox reactions involved in energy production
- Acting as a substrate for enzymes that regulate cellular processes
NAD+ supports the generation of ATP through metabolic pathways. It’s involved in modifying proteins via enzymes like sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs). It links cellular energy status to downstream processes that help cells respond to environmental and metabolic stress.
NAD+ is studied in relation to several biological features commonly observed during cellular senescence, including:
- Genomic maintenance – Involves enzymes that require NAD+ to function
- Epigenetic regulation – NAD+-dependent enzymes influence gene expression through chromatin remodeling
- Mitochondrial activity – NAD+ is essential for energy production and mitochondrial quality control
- Autophagy – NAD+ supports recycling of cellular components
Enzymes that consume NAD+, like CD38 and PARPs, may increase in activity over time. The salvage pathway, which recycles NAD+, relies on enzymes like NAMPT, whose levels may decrease with age. This imbalance between NAD+ consumption and recycling is a subject of active research.
Molecular Formula
C21H27N7O14P2
Molecular Weight
663.4 g/mol
Biochemical ID
PubChem CID: 5892
Alternatives Names
nadide, coenzyme I, beta-NAD
The NAD+ sold by Peptide Systems is not FDA-approved and is ONLY available for research and laboratory purposes only. You must read, agree to and adhere to our Terms and Conditions before making an order.
NAD+
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CERTIFIED by 3rd party, US registered labs with ISO 17025:2017 certification
- Certified sterile.
- Certified free of microbial contaminants (endotoxin, LPS, LAL).
- Certified free of chemical contaminants (TFA, IEX).
- Certified peptide identity (HPLC, LC-MS).
- Certified >99% pure (HPLC).
