BPC-157 + TB-500
Certificate of Analysis (COA) data included in product images.
Purity: ≥ 99 % (HPLC verified)
Sterility: Confirmed (sterile-filtered)
Endotoxins (LPS): Not detected
Trifluoroacetic Acid (TFA): Not detected (LC-MS verified)
Identity: Confirmed (LC-MS verified)
Quantity: Verified (HPLC analysis)
Format: Lyophilized powder sealed in an airtight vial. Lyophilization enhances peptide stability during storage.
Pricing
Quantity | Price/Vial | Savings |
---|---|---|
1 vial | $99 | — |
2 vials | $95 | Save 4 % |
3 vials | $91 | Save 8 % |
4 vials | $87 | Save 12 % |
5 vials | $85 | Save 16 % |
Product Overview
BPC-157 (Body Protection Compound-157) is a 15-amino-acid peptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) first identified by Dr. Predrag Sikiric in 1991 from gastric tissue extracts. More than 180 peer-reviewed studies have explored its interactions with fibroblasts, endothelial cells, and inflammatory mediators in non-clinical models.
Molecular Formula: C₆₂H₉₈N₁₅O₂₂
Molecular Weight: 556 g/mol
PubChem CID: 9941957
TB-500 (Thymosin Beta-4 Fragment)
TB-500 is a synthetic peptide identical in amino-acid sequence to thymosin beta-4 (Tβ4), an actin-binding protein widely studied for its roles in cell migration, cytoskeletal regulation, and inflammation control. Tβ4 has been described in over 900 scientific papers; TB-500 itself has appeared in 11 peer-reviewed publications as a research analog.
Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight: 4408 g/mol
PubChem CID: 62707662
Biological Background (For Research Context Only)
BPC-157 Mechanistic Insights
In laboratory models, BPC-157 has been investigated for cell-protective and anti-inflammatory actions that appear to influence several signaling systems:
Activation of VEGFR2 → Akt → eNOS pathways associated with endothelial repair and microvascular stability.
Modulation of growth hormone receptor (GHR) → JAK2 signaling in fibroblast cultures, studied in connection with collagen formation and wound-model tissue remodeling.
Regulation of nitric-oxide (NO) balance and up-regulation of antioxidant enzymes such as heme oxygenase-1 (HO-1), often cited as part of its anti-oxidative and cytoprotective profile.
In preclinical injury and inflammation models, BPC-157 has been observed to reduce pro-inflammatory cytokine expression and support tissue regeneration processes via enhanced fibroblast migration and angiogenesis.
TB-500 (Thymosin Beta-4) Mechanistic Insights
TB-500 is frequently used in research exploring cellular motility, inflammation modulation, and repair biology:
Influences actin polymerization, aiding in cell structure organization and migration during tissue-model experiments.
Interacts with integrins and VEGF signaling, pathways known to participate in angiogenesis and matrix remodeling.
Demonstrates down-regulation of inflammatory mediators and up-regulation of repair-related genes in non-clinical wound-healing models.
Alternate Names
BPC-157: Body Protection Compound-157
TB-500: Thymosin Beta-4 Fragment
Storage & Handling
Store at 4 °C in a dry, light-protected environment for medium-term storage. Reconstitute with sterile, bacteriostatic solvent immediately before use. Proper storage maintains peptide integrity. Lyophilized BPC/TB can be stored at 4 °C for months, while reconstituted BPC/TB needs to be used within 3-4 weeks while stored at 4 °C.
Intended Use and Compliance
All peptide products from Peptide Systems are supplied for laboratory and scientific research use only. They are not approved by the FDA and not intended for human or veterinary consumption.
Purchase implies agreement to our full Terms and Conditions, including all research-use and compliance policies.
References & Further Reading
BPC-157 in Musculoskeletal Injuries- https://pmc.ncbi.nlm.nih.gov/articles/PMC12446177/
BPC 157 in spinal cord injury - https://josr-online.biomedcentral.com/articles/10.1186/s13018-019-1242-6
Thymosin β4 Prevents Oxidative Stress, Inflammation, and Fibrosis - https://pmc.ncbi.nlm.nih.gov/articles/PMC6079392/
BPC 157 for Multiple Types of Knee Pain - https://pubmed.ncbi.nlm.nih.gov/34324435/
Peptides in Soft Tissue Regeneration - https://pmc.ncbi.nlm.nih.gov/articles/PMC11426299/
BPC-157 + TB-500
Buy 5 vials get 16% off
CERTIFIED by 3rd party, US labs with ISO 17025:2017 certification
- Certified sterile.
- Certified free of microbial contaminants (endotoxin, LPS, LAL).
- Certified free of chemical contaminants (TFA, IEX).
- Certified peptide identity (HPLC, LC-MS).
- Certified >99% pure (HPLC).